Diagnostic Marker for Myocardial Infaction”, 2010
Example : IMA급성심근경색증 diagnosis (acute myocardial infarction)
Requirement of ideal cardiac marker for IMA diagnosis
Existing in cardiac muscle - not any other parts of the body.
Fast emission when the cell is damaged.
Quantity of released markers should be in direct proprotion to size of enzyme.
Easy to assay, stab
Definition and Biochemistry
of Lectins
Structure : Origin protein + 탄수화물 (ligand)
· Sources of lectins : Animals, plants, bacteria
· Grouping ; by their preferential binding to the type
D-pyranose sugars
by dependent ; C-type or S-type
Lectin as Diagnostic Probes
Binding specificities
Ex ) Covavlin A(Con A) – Gluc
1. Heart disease & cardiac enzymes
1.1 heart disease
Team#5 has had researches about diagnosis of cardiovascular disease using cardiac marker (cardiac enzyme). Cardiovascular disease (heart disease) is a class of diseases that involve the heart or blood vessels (arteries and veins). Cardiovascular diseases remain the biggest cause of deaths worldwide, through over the last two decades, cardio
5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
Review of systems
Urogenital
Dysuria (-), Frequency (-), Nocturia (-)
Urgency (-), Oligouria(-), Hematuria (-)
Musculoskeletal
Muscle or joint pain (-), Limitation in motor activity (-)
Backache (-)
Skin
Rashes (-), Eruption (-), Jaundice (-), Itching (-), Lumps (-), Changes in hair or nails (-)
General status
V/S
BP : 110/80mmHg – PR : 64/min – RR : 20/mi
1. Graves’ disease
-antithyroid drug: PTU, carbimazole, methimazole
-radioiodine: 131I
2. Acute Gastro-Enteritis
-GFS f/u
Thyrotoxicosis is defined as the state of thyroid hormone excess and is not synonymous with hyperthyroidism
But, the major etiologies of thyrotoxicosis are hyperthyroidism caused by Grave’s disease, toxic MNG, and toxic adenomas
2. Pathogenesis (cont.)
(1) 296.2x 주요 우울장애, 단일 삽화의 진단기준
A. 단 한 번의 주요 우울증 삽화가 나타난다.
B. 주요 우울증 삽화가 분열정동장애로 더 잘 설명되지 않으며, 정신분열증, 정신분열형 장 애, 망상장애 또는 달리 분류되지 않는 정신증적 장애와 겹쳐서 나타나는 것이 아니다.
C. 조증 삽화, 혼재성 삽